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RITUXIMAB IN PEDIATRIC RHEUMATOLOGY

The article presents literature review on the role of B-lymphocytes in pathogenesis of rheumatologic diseases and on the administration of chimeric anti-CD20 monoclonal antibodies — rituximab — for treatment of systemic lupus erythematosus, systemic vasculitis, juvenile dermatomyositis, and juvenile... Full description

Main Author: E.I. Alexeeva
Contributors: R.V. Denisova | Author
S.I. Valieva | Author
T.M. Bzarova | Author
A.O. Lisitsyn | Author
Contained in: Voprosy Sovremennoj Pediatrii (01.01.2010)
Journal Title: Voprosy Sovremennoj Pediatrii
Fulltext access: Fulltext access (direct link - free access)
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Links: Additional Link (doaj.org)
Additional Link (vsp.spr-journal.ru)
Fulltext access (doaj.org)
Fulltext access (doaj.org)
ISSN: 1682-5527
Language: English
Russian
Physical Description: Online-Ressource
PPN (Catalogue-ID): DOAJ021795134
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Internes Format
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520 |a The article presents literature review on the role of B-lymphocytes in pathogenesis of rheumatologic diseases and on the administration of chimeric anti-CD20 monoclonal antibodies — rituximab — for treatment of systemic lupus erythematosus, systemic vasculitis, juvenile dermatomyositis, and juvenile arthritis in children. Results of studies showed that rituximab has good tolerability, efficacy and safety in children’s rheumatologic practice.Key words: children, B-lymphocytes, rituximab, treatment, depletion. 
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