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POST MYOCARDIAL INFARCTION VENTRICULAR SEPTAL RUPTURE AND FACTORS ASSOCIATED WITH ITS MORTALITY: A RETROSPECTIVE STUDY

OBJECTIVES: To determine the incidence of ventricular septal rupture (VSR) following acute myocardial infarction (AMI) and to find out factors associated with its mortality. METHODS: This retrospective study was done at Lady Reading Hospital, Peshawar, Pakistan in which 03years (January-2014 to Dece... Full description

Main Author: Muhammad Adil
Contributors: Zohaib Ullah Zahid | Author
Muhammad Saad Jibran | Author
Shahzeb | Author
Muhammad Irfan | Author
Contained in: Khyber Medical University Journal (01.09.2018)
Journal Title: Khyber Medical University Journal
Fulltext access: Fulltext access (direct link - free access)
Availability is being checked...
Interlibrary loan: Check possibility for interlibrary loan
Links: Additional Link (doaj.org)
Additional Link (www.kmuj.kmu.edu.pk)
Fulltext access (doaj.org)
Fulltext access (doaj.org)
ISSN: 2305-2643
Language: English
Physical Description: Online-Ressource
PPN (Catalogue-ID): DOAJ037613960
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Internes Format
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100 0 |a Muhammad Adil  |e verfasserin  |4 aut 
245 1 0 |a POST MYOCARDIAL INFARCTION VENTRICULAR SEPTAL RUPTURE AND FACTORS ASSOCIATED WITH ITS MORTALITY: A RETROSPECTIVE STUDY  |h Elektronische Ressource 
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520 |a OBJECTIVES: To determine the incidence of ventricular septal rupture (VSR) following acute myocardial infarction (AMI) and to find out factors associated with its mortality. METHODS: This retrospective study was done at Lady Reading Hospital, Peshawar, Pakistan in which 03years (January-2014 to December-2016) data of AMI patients was studied. Patients with VSR after AMI, diagnosed on echocardiography were included. Chi-square test was applied to correlate cardiovascular risk factors and clinical parameters with the mortality in post-MI VSR patients. RESULTS: A data of 6240 patients with AMI was analyzed in which 60 patients had VSR (incidence rate of 0.96%) with 64.7% having acute anterior MI. It is 8.5 times greater in first-MI and have a delayed onset. Twenty-six patients were excluded due to presence of concomitant complications and rest of 34 were studied in detail. Mean age of post-MI VSR patients was 63.21±8.9years, among them 52.9% were males. Mean time of development of VSR was 4.1±2.2days with the minimum of 01day and maximum of 10days after diagnosis of AMI. Nineteen patients (55.9%) didn’t receive streptokinase. The mortality rate was 38.2% which was significantly associated with diabetes, tachycardia, shock, high Killip class, renal impairment and multiple VSR’s (P-value of 0.012, 0.021, 0.032, 0.031, 0.036, and 0.016 respectively). CONCLUSIONS: VSR incidence after AMI in our study was 0.96% with 8.5 times greater in first-MI and have a delayed onset. Diabetes mellitus, multiple lesions, presence of shock, tachycardia, renal impairment and high Killip class after development of VSR are associated with high mortality. 
700 0 |a Zohaib Ullah Zahid  |e verfasserin  |4 aut 
700 0 |a Muhammad Saad Jibran  |e verfasserin  |4 aut 
700 0 |a Shahzeb  |e verfasserin  |4 aut 
700 0 |a Muhammad Irfan  |e verfasserin  |4 aut 
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856 4 0 |y DOAJ  |u https://doaj.org/article/e8711fb044ce44c5a126d1446c5eb6d8 
856 4 0 |u http://www.kmuj.kmu.edu.pk/article/view/18071/pdf 
856 4 0 |u https://doaj.org/toc/2305-2643 
856 4 0 |u https://doaj.org/toc/2305-2651 
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951 |a AR 
952 |j 2018  |b 01  |c 09