New method for bioavailability assessment of slow-release preparations of theophylline

Abstract Variability in an individual's clearance of theophylline is an important consideration when estimating bioavailability. A method is described for compensating for this problem, using the serum concentration of theophylline and urinary excretion data on its major metabolites to make an...
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Publication:

1985

Contained In:

Journal of Pharmacokinetics and Biopharmaceutics - 13(1985), 6 vom: 01. Dez., Seite 571-587

Contributors:

Kasuya, Yasuji [Author]
Ohno, Tetsuro [Author]
Kubota, Noriyoshi [Author]
Takahashi, Hidenori [Author]
Hirayama, Hiroki [Author]

Media Type:

Electronic Article

Links:

Volltext [Lizenzpflichtig]

Language:

English

doi:

10.1007/BF01058902

PPN (Catalogue-ID):

SPR014700174